Ampiclox Dosage of Ampicillin ဆေး လူကြီး-ကလေး ဘယ်လောက်ပေးရသလဲ
Capsules ဆေးတောင့်
250 mg
500 mg
Oral Suspension ဆေးရည်
125 mg/5 ml
250 mg/5 ml
Powder for injection ထိုးဆေး
125 mg
250 mg
500 mg
1 g
2 g
10 g (adult dosing only)
Dosing Considerations ဘယ်လောက်ပေးရသလဲ
Adults: လူကြီး
Orally: 250-500 mg every 6 hours
Intravenously/intramuscularly: 1-2 g every 4-6 hours or 50-250 mg/kg/day divided every 4-6 hours, not to exceed 12 g/day
Pediatric: ကလေး
400 mg/kg/day intravenously/intramuscularly divided every 6 hours
50-100 mg/kg/day orally divided every 4-6 hours, not to exceed 12 g/day
Severe infection: 200-400 mg/kg/day intravenously/intramuscularly divided every 6 hours
Potential toxic dose: Children under 6 years: 300 mg/kg
Neonates under 28 days: မွေးကင်းစ
Under 7 days:
Infants under 2 kg: 50-100 mg/kg/day intravenously/intramuscularly divided every 12 hours
Infants over 2 kg: 75-150 mg/kg/day intravenously/intramuscularly divided every 8 hours
Infants under 1.2 kg: 50-100 mg/kg/day intravenously/intramuscularly divided every 12 hours
Infants 1.2-2 kg: 75-150 mg/kg/day intravenously/intramuscularly divided every 8 hours
Infants over 2 kg: 100-200 mg/kg/day intravenously/intramuscularly divided every 6 hours
Endocarditis Prophylaxis နှလုံးကြွက်သားရောင်ခြင်းအား ကာကွယ်ရန်
Adults: လူကြီး
2 g intravenously/intramuscularly (with or without gentamicin 1.5 mg/kg for gastrointestinal/genitourinary) within 30-60 minutes before procedure
Dosing considerations
American Heart Association guidelines recommend only for high-risk patients
Pediatric: ကလေး
50 mg/kg intravenously/intramuscularly (with or without gentamicin 1.5 mg/kg for gastrointestinal/genitourinary) within 30-60 minutes before the procedure
Dosing considerations:
American Heart Association guidelines recommended only for high-risk patients
Endocarditis
12 g/day continuous intravenous infusion or divided every 4 hours
Genitourinary Tract Infections (excluding Gonorrhea)
Adults:
1-2 g intravenously every 6 hours with gentamicin if enterococcus suspected
Pediatric:
Children under 40 kg: 50-100 mg/kg/day intravenously/intramuscularly divided every 6 hours
Children over 40 kg: 500 mg intravenously/intramuscularly divided every 6 hours
Gastrointestinal Tract Infections
Adults:
500 mg intravenously every 6 hours; larger doses may be necessary for severe or chronic infection
Pediatric:
Children under 20 kg: 50-100 mg/kg/day orally divided every 6 hours
Children over 20 kg: 500 mg orally every 6 hours
Children under 40 kg: 50 mg/kg/day intravenously/intramuscularly divided every 6-8 hours
Children over 40 kg: 500 mg intravenously/intramuscularly every 6 hours
Gonorrhea
Adults:
3.5 g intravenously administered once simultaneously with 1 g of probenecid
Pediatric:
Children under 20 kg: safety and efficacy not established
Children over 20 kg: 3.5 g orally administered once simultaneously with 1 g of probenecid
Respiratory Tract Infections
Adults:
250 mg intravenously every 6 hours
Pediatric:
Children under 20 kg: 50 mg/kg/day orally divided every 6-8 hours
Children over 20 kg: 250 mg orally every 6 hours
Children under 40 kg: 25-50 mg/kg/day intravenously/intramuscularly divided every 6-8 hours
Children over 40 kg: 250-500 mg intravenously/intramuscularly every 6 hours
Bacterial Meningitis
150-200 mg/kg/day intravenously every 6-8 hours
Group B Streptococcus
Neonatal prophylaxis
2 g intravenously initially, followed by every 4 hours until delivery
Listeria Infection
2 g intravenously every 4 hours
Cholera
Pediatric:
50 mg/kg/day orally divided every 6 hours for 3 days; not to exceed 2 g/day
Administration
Take oral dosage form on an empty stomach
Dosing Modifications
Renal Impairment
Creatinine Clearance less than 10 ml/min: administer every 12-24 hours
Creatinine Clearance 10-50 ml/min: administer every 6-12 hours
Creatinine Clearance over 50 ml/min: administer every 6 hours
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